UNDERSTANDING THE ALLOSTERIC TRIGGER FOR THE FRUCTOSE-1,6-BISPHOSPHATE REGULATION OF THE ADP-GLUCOSE PYROPHOSPHORYLASE FROM ESCHERICHIA COLI
UNDERSTANDING THE ALLOSTERIC TRIGGER FOR THE FRUCTOSE-1,6-BISPHOSPHATE REGULATION OF THE ADP-GLUCOSE PYROPHOSPHORYLASE FROM ESCHERICHIA COLI by Carlos Maria Figueroa Abstract ADP-glucose pyrophosphorylase is the enzyme responsible for the regulation of glycogen synthesis in bacteria. The enzyme N-terminal domain has a Rossmann-like fold with three neighbor loops facing the substrate ATP. In the Escherichia coli…